Flow Cytometry Lab Scientist

Kelly Science and Clinical FSP is currently seeking a Flow Cytometry Scientist for a long term engagement in Spring House, PA with one of our Global clients. This person will join our Kelly FSP (Functional Service Provider) division, a managed solution provider and business unit of Kelly Services, Inc. This role is full-time and is offering full benefit options. As a Kelly FSP employee you may be eligible for Medical, Dental, Vision, 401K and a variety of other benefits to choose from. You may also be eligible for paid time off, including holiday, vacation, and sick/personal time.

Lab-based flow cytometry scientist

Position Summary

We are seeking a passionate and talented scientist, as a contractor, to join the Clinical Cytometry group within Biomarker Development & Operations in Spring House, PA. This role will support client Oncology clinical programs by delivering fit-for-purpose flow cytometry biomarker assays and high-quality clinical data in a highly collaborative clinical research environment.

The successful candidate will be lab-based and should have experience with flow cytometry, primary cell handling, and cell-based assays. The role will focus on designing and executing robust ex vivo flow cytometric assays with immunophenotyping and functional readouts. Hands-on experience with clinical flow cytometry assay development, optimization, analytical validation and clinical sample analysis is highly valued.

 

Primary responsibilities (including, but are not limited to):

 

1. Execute multi-parameter clinical flow cytometry biomarker assays end-to-end including assay development, optimization, fit-for-purpose validation, on-time assay deployment for clinical sample testing, and downstream analysis

2. Design, develop, and perform robust ex vivo and in vitro cell-based assays that incorporate functional readouts, including activation, proliferation, cytokine production, and cytotoxicity

3. Handle and isolate primary human cells from blood and cryopreserved specimens for characterization and functional assessment

4. Record experimental data and results accurately and well-organized following SOPs and internal document requirements including writing validation reports

5. Demonstrate the ability to analyze, interpret, and present data in professional 'publication ready' format

6. Demonstrate clear and professional verbal and written communication and effectively present scientific data and concepts

7. Support clinical flow cytometry research projects implemented externally at external service providers/CROs.

8. Monitor data quality resulting from outsourced clinical flow cytometry assays. Perform assay troubleshoot to correct errors, identify root-cause of errors and prevent re-occurrence.

9. Work independently and manage multiple projects simultaneously

10. Demonstrate the ability to contribute to various projects outside of his/her own, and collaborate with stakeholders from all relevant functions

 

Qualifications

 

• Education: A B.S. with 3+ years, a M.S. with 2+ years, or a PhD in biomedical sciences with 1+ year of flow cytometry laboratory experiences are required. Pharmaceutical/biotech industry experience is a plus but not necessary. Related Experience:
• Extensive hands-on experience in developing, validating, implementing and testing high-dimensional flow cytometry assays is required. The candidate should be versed in the analysis of such multi-dimensional flow cytometry experiments with the appropriate instruments (BD/Waters & Cytek preferred) and software (particularly FlowJo, OMIQ) and ability to learn new analytical software packages. Experience with FACS cell sorting is not necessary but valuable.
• Proficiency in PBMC/BMMC isolation and cryopreservation is required. Experience with primary cell culture techniques is required. Expertise in immune cell isolation from whole blood, tissues or tumor dissociation is a plus.
• Background in Oncology and/or Immunology is desirable, as well as the ability to understand and willingness to integrate current scientific literature into research practice.
• Experience with managing research projects at clinical flow cytometry specialty labs/CROs including assay development, analytical validation, and assay implementation is highly valuable Personal Skills:
• Flexibility and interest in learning/developing new techniques and skills in accordance with the research program needs
• Position requires ability to work independently and as part of a larger team. Therefore, excellent communication skills, both written and verbal, and strong interpersonal skills are necessary.

As part of our promise to talent, Kelly supports those who work with us through a variety of benefits, perks, and work-related resources. Kelly offers eligible employees voluntary benefit plans including medical, dental, vision, telemedicine, term life, whole life, accident insurance, critical illness, a legal plan, and short-term disability.

As a Kelly employee, you will have access to a retirement savings plan, service bonus and holiday pay plans (earn up to eight paid holidays per benefit year), and a transit spending account. In addition, employees are entitled to earn paid sick leave under the applicable state or local plan.

Click here for more information on benefits and perks that may be available to you as a member of the Kelly Talent Community.